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Seroprevalence of hepatitis B virus co-infection among HIV-1-positive patients in North-Central Nigeria: The urgent need for surveillance

Terver M. Akindigh, Abba O. Joseph, Chrisitiana O. Robert, Ocheme J. Okojokwu, Juliet N. Okechalu, Aje J. Anejo-Okopi
African Journal of Laboratory Medicine | Vol 8, No 1 | a622 | DOI: https://doi.org/10.4102/ajlm.v8i1.622 | © 2019 Terver M. Akindigh, Abba O. Joseph, Christiana O. Robert, Ocheme J. Okojokwu, Juliet N. Okechalu, Joseph A. Anejo-Okopi | This work is licensed under CC Attribution 4.0
Submitted: 09 March 2017 | Published: 27 June 2019

About the author(s)

Terver M. Akindigh, Infectious Diseases Unit, Jos University Teaching Hospital, Jos, Nigeria
Abba O. Joseph, Infectious Diseases Unit, Jos University Teaching Hospital, Jos, Nigeria
Chrisitiana O. Robert, Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Nigeria
Ocheme J. Okojokwu, Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Nigeria
Juliet N. Okechalu, Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Nigeria
Aje J. Anejo-Okopi, Department of Microbiology, Faculty of Natural Sciences, University of Jos, Jos, Nigeria


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Abstract

We report the seroprevalence of hepatitis B surface antigen among HIV-positive patients at a clinic in North-Central Nigeria. Screening for hepatitis B virus was based on serological markers. Alanine aminotransferase levels and CD4+ T-lymphocyte counts were compared between patients. The study showed that 9.2% were positive for hepatitis B surface antigen with significant differences between alanine aminotransferase levels of patients with and without hepatitis B virus. We recommend a national surveillance system to monitor control efforts.

Keywords

Antiretroviral therapy; Alanine aminotransferase; CD4+ T-lymphocytes; hepatitis B virus; HIV; Serological markers

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