Brief Report

Hyperuricaemia is associated with dyslipidemia but not HbA1c among type 2 diabetes mellitus patients in Botswana

Ellen Gobusamang, Naledi G. Nyepetsi, Modisa S. Motswaledi, Ishmael Kasvosve
African Journal of Laboratory Medicine | Vol 8, No 1 | a786 | DOI: https://doi.org/10.4102/ajlm.v8i1.786 | © 2019 Ellen Gobusamang, Naledi G. Nyepetsi, Modisa S. Motswaledi, Ishmael Kasvosve | This work is licensed under CC Attribution 4.0
Submitted: 07 February 2018 | Published: 07 November 2019

About the author(s)

Ellen Gobusamang, Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Botswana, Gaborone, Botswana
Naledi G. Nyepetsi, Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Botswana, Gaborone, Botswana
Modisa S. Motswaledi, Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Botswana, Gaborone, Botswana
Ishmael Kasvosve, Department of Medical Laboratory Sciences, Faculty of Health Sciences, University of Botswana, Gaborone, Botswana


Share this article

Bookmark and Share

Abstract

Medical records and residual samples from 334 type 2 diabetes mellitus patients attending a clinic in Gaborone, Botswana, during the period September–December 2016 were analysed for the effects of hyperuricaemia on biochemical markers of adverse outcomes. The patients were stratified as having hyperuricaemia (> 400 µmol/L) or normal serum uric acid (≤ 400 µmol/L). We compared glycated haemoglobin, triglycerides, low-density lipoprotein-cholesterol, high-density lipoprotein-cholesterol, total cholesterol and serum creatinine between the two serum uric acid categories. Hyperuricaemia was detected in 28% of patients (95% confidence interval 23.1–32.9) and was associated with increased serum triglycerides, triglyceride to high-density lipoprotein-cholesterol ratio and creatinine concentration, but not with glycated haemoglobin.

Keywords

Hyperuricaemia; Diabetes mellitus; HbA1C; Lipids; Africans

Metrics

Total abstract views: 69
Total article views: 33


Crossref Citations

No related citations found.